123Buttons.com

Death and hypnosis: two remarkable cases.

Am J Clin Hypn. 2008 Jul;51(1):69-75

Authors: Ewin DM

The Journal of the American Medical Association reported The First Recorded Death in Hypnosis in its issue of October 27, 1894. Ninety-nine years later, on September 23, 1993 a healthy 24-year old mother of two was found dead at home, fully clothed and draped across the foot of one of her children’s bed, 5 hours after volunteering as a subject for a stage hypnosis show. The suggestion given to terminate the trance had been that when the hypnotist said, “Goodnight”, several subjects would feel 10,000 volts of electricity through the seat of their chairs. Unknown to the hypnotist, she had been phobic about electricity ever since a childhood shock, and would not even change a light bulb or plug in a cord. The coroner’s verdict was death by natural causes.

PMID: 18714893 [PubMed - in process]

More: continued here

Filed under: Hypnosis | No Comments »

[Correlated activity of neurons in the sensorimotor cortex of rabbits in the state of defensive dominanta and “animal hypnosis”]

Zh Vyssh Nerv Deiat Im I P Pavlova. 2008 Mar-Apr;58(2):183-93

Authors:

A hidden excitation focus (dominanta focus) was produced in the rabbit’s CNS by threshold electrical stimulation of the left forelimb with the frequency of 0.5 Hz. As a rule, after the formation of the focus, pairs of neurons with prevailing two-second rhythm in their correlated activity were revealed both in the left and right sensorimotor cortices (with equal probabilities 29.3 and 32.4%, respectively). After “animal hypnosis” induction, the total percent of neuronal pairs with the prevalent dominanta-induced rhythm decreased significantly only in the right hemisphere (21%). After the termination of the “animal hypnosis” state, percent of neuronal pairs in the right cortex with prevailing two-second rhythm significantly increasead if the neurons in a pair were neighboring and decreased if they were remote from each other. Similar changes after the hypnotization were not found in the left cortex. Analysis of correlated activity of neuronal pairs with regard to amplitude characteristics showed that for both the right and left hemispheres, the prevalence of the two-second rhythm was more frequently observed in crosscorrelation histograms constructed regarding discharges of neurons with the lowest spike amplitude (in the right hemisphere) or the lowest and mean amplitudes (in the left hemisphere) selected from multiunit records.

PMID: 18661780 [PubMed - in process]

More: continued here

Filed under: Hypnosis | No Comments »

Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility.

Anesth Analg. 2008 Aug;107(2):494-506

Authors: Hendrickx JF, Eger EI, Sonner JM, Shafer SL

BACKGROUND: Drug interactions may reveal mechanisms of drug action: additive interactions suggest a common site of action, and synergistic interactions suggest different sites of action. We applied this reasoning in a review of published data on anesthetic drug interactions for the end-points of hypnosis and immobility. METHODS: We searched Medline for all manuscripts listing propofol, etomidate, methohexital, thiopental, midazolam, diazepam, ketamine, dexmedetomidine, clonidine, morphine, fentanyl, sufentanil, alfentanil, remifentanil, droperidol, metoclopramide, lidocaine, halothane, enflurane, isoflurane, sevoflurane, desflurane, N(2)O, and Xe that contained terms suggesting interaction: interaction, additive, additivity, synergy, synergism, synergistic, antagonism, antagonistic, isobologram, or isobolographic. When available, data were reanalyzed using fraction analysis or response surface analysis. RESULTS: Between drug classes, most interactions were synergistic. The major exception was ketamine, which typically interacted in either an additive or infra-additive (antagonistic) manner. Inhaled anesthetics typically showed synergy with IV anesthetics, but were additive or, in the case of nitrous oxide and isoflurane, possibly infra-additive, with each other. CONCLUSIONS: Except for ketamine, IV anesthetics acting at different sites usually demonstrated synergy. Inhaled anesthetics usually demonstrated synergy with IV anesthetics, but no pair of inhaled anesthetics interacted synergistically.

PMID: 18633028 [PubMed - in process]

More: continued here

Filed under: Hypnosis | No Comments »

[Hypnosis and pain perception]

Rev Med Liege. 2008 May-Jun;63(5-6):424-8

Authors: Vanhaudenhuyse A, Boveroux P, Boly M, Schnakers C, Bruno MA, Kirsch M, Demertzi A, Lamy M, Maquet P, Laureys S, Faymonville ME

Improvement in functional neuroimaging allows researchers to disentangle the brain mechanisms involved in the pain modulation encountered during hypnosis. It has been shown that the anterior cingulate and prefrontal cortices are important in the modulation of incoming sensory and noxious input. Moreover, clinical studies in certain types of surgery (eg thyroidectomy, mastectomy and plastic surgery) have demonstrated that hypnosis may avoid general anesthesia.

PMID: 18669215 [PubMed - in process]

More: continued here

Filed under: Hypnosis | No Comments »

The Effect of Hypnosis on Systemic and Rectal Mucosal Measures of Inflammation in Ulcerative Colitis.

Am J Gastroenterol. 2008 May 28;

Authors: Mawdsley JE, Jenkins DG, Macey MG, Langmead L, Rampton DS

OBJECTIVES: Hypnotherapy is effective in several diseases with a psychosomatic component. Our aim was to study the effects of one session of hypnosis on the systemic and rectal mucosal inflammatory responses in patients with active ulcerative colitis (UC). METHODS: In total, 17 patients with active UC underwent a 50-min session of gut-focused hypnotherapy. Before and after each procedure, the systemic inflammatory response was assessed by serum interleukin (IL)-6 and IL-13 concentrations, tumor necrosis factor-alpha (TNF-alpha) and IL-6 production by lipopolysaccharide (LPS)-stimulated whole blood, leukocyte count, natural killer (NK) cell number, platelet activation, and platelet-leukocyte aggregate formation. Rectal inflammation was assessed by mucosal release of substance P (SP), histamine, IL-13 and TNF-alpha, reactive oxygen metabolite production, and mucosal blood flow. Eight patients with active UC underwent a control procedure. RESULTS: Hypnosis decreased pulse by a median 7 beats per minute (bpm) (P= 0.0008); it also reduced the median serum IL-6 concentration by 53% (P= 0.001), but had no effect on the other systemic variables assessed. Hypnosis reduced rectal mucosal release of SP by a median 81% (P= 0.001), histamine by 35% (P= 0.002) and IL-13 by 53% (P= 0.003), and also, blood flow by 18% (P= 0.0004). The control protocol had no effect on any of the variables assessed. CONCLUSIONS: Hypnosis reduced several components of the systemic and mucosal inflammatory response in active ulcerative colitis toward levels found previously in the inactive disease. Some of these effects may contribute to the anecdotally reported benefits of hypnotherapy and provide a rationale for controlled trials of hypnotherapy in UC.

PMID: 18510607 [PubMed - as supplied by publisher]

More: continued here

Filed under: Hypnosis | No Comments »